Pseudomonas aeruginosa is an aerobic, gram negative bacterium. It is saprophytic and usually grows in moist environment like water, plants and soil. In hospitals and wards, it usually grows on tubings, water sinks, antiseptic and sterilizing solutions, etc. It is an opportunistic organism and therefore, a common cause of nosocomial infections. It can lead to serious and life threatening diseases in immunocompromised individuals.
Pseudomonas is a number cause of nosocomial pneumonia and ICU related pneumonia. In healthy individuals, it usually causes otitis externa, oteomyelitis, cellulitis and urinary tract infections; in immunocompromised individuals it leads to pneumonia, meningitis, sepsis, endocarditis, wound infection, urinary tract infection, erythema gangrenosum, etc. (Guideline on Multiple-drugs Resistant Pseudomonas aeruginosa (MRPA), 2004).
Infections are a leading cause of morbidity and mortality in burns patients. Gram negative organisms like pseudomonas cause serious infections in burns patients resulting in 50% increase in the mortality rates as compared to those patients who do not have gram negative infection (Weber).