The high risk groups for JEV are children and young adults, where children between 3 to 15 years are 10 times more likely to get infected than adults. The elderly, chronically sick, those with immunosuppressant diseases are also more likely to get infected. The infected will often show symptoms ranging from malaise, meningoencephalitis, seizures and death.
JEV infection also characterized by febrile illness that is non-specific or by aseptic meningitis. The most serious type of JEV is Meningo-encephalitis that has a death rate of 5 to 35 percent; survivors of this type end up with serious neurological sequelae depicted by ataxia, paralysis, tremors, loss of memory, behavior disorder and impaired cognition. After infection, humans are exposed to a 4 to 14 day incubation period where they suffer a few days of fever, coryza and rigors.
 Solomon, T., Dung, M.N., Kneen, R., Gainsborough, M., Vaughn, D.W. and Khanh, V.T. Japanese Encephalitis (J. Neurol. Neurosurg. Psychiatry, 68, 2000) 414.
 Tiroumourougane, S.V., Raghava, P. and Srinivasan, S. Japaneseviral Encephalitis (Postgrad. Med. J. 78, 2002) 207.